The end of the Vanquish's production run was celebrated with the Vanquish Ultimate Edition. Aston Martin announced that the last 40 cars built would have a new 'Ultimate Black exterior color, upgraded interior, and personalized sill plaques. More significantly, the Ultimate Edition was the first Vanquish to be offered with a conventional stick-shift manual transmission. The auto-shift manual gearbox in the original Vanquish has been widely criticized (perhaps most infamously by Jeremy Clarkson on the BBC's Top Gear program), so this change was greeted with approval by the automotive press. Aston Martin offered to retrofit the new gearbox to any Vanquish, for a cost of £13,250.
Aston Martin was frequently rumoured to be considering a roadster version of the Vanquish, especially in response to the Ferrari 550 Barchetta Pininfarina, but no such version ever emerged. The Vanquish was the basis of two concept cars, both shown at the International Geneva Motor Show in 2004, the Zagato Roadster (a 2-seat roadster) and the Bertone Jet 2 (a 2-door shooting brake). Vanquish production ended on 19 July 2007, coinciding with the shutting of the company's Newport Pagnell factory after 49 years of operation.
The last car was a Vanquish S Ultimate Edition in black.